Title: Elucidating the role of microbiome in health and disease using multi-omics and systems biology approaches
Dr Clasen completed his undergraduate and master’s studies in bioinformatics and biotechnology at the University of Pretoria in South Africa. He then moved to London to pursue a PhD in bioinformatics and systems biology at the Francis Crick Institute and King’s College London. During his PhD he developed computational mathematical models to simulate metabolism with a specific focus on liver disease and liver cancer. This included tissue-specific and whole-body integrative genome-scale metabolic models of host and microbiome. Currently, he is a Research Associate at the Centre for Host-Microbiome Interactions at King’s College London where his research focusses on the development of computational frameworks for a deeper mechanistic understanding of the functional role of the microbiome in the pathophysiology of complex human diseases. Most of these projects are translational in nature that involves biomarker identification as well as the design of novel diagnostic and therapeutic avenues.